Cliniques universitaires Saint-Luc deploys an on-premises Qwen3-235B assistant inside its Epic EHR
Cliniques universitaires Saint-Luc· BelgiumQwen3-235B · vLLM · LiteLLM +5A Brussels university hospital hosts a GDPR-compliant LLM assistant on-site on a server with 8 NVIDIA H200 GPUs, using Qwen3-235B, vLLM, LiteLLM, Open WebUI and retrieval over EHR documents and literature. After a one-month pilot with 28 physicians, it was deployed hospital-wide and adopted by 1,028 users who generated 14,910 conversations over five months.
Overview
A Brussels university hospital hosts a GDPR-compliant LLM assistant on-site on a server with 8 NVIDIA H200 GPUs, using Qwen3-235B, vLLM, LiteLLM, Open WebUI and retrieval over EHR documents and literature. After a one-month pilot with 28 physicians, it was deployed hospital-wide and adopted by 1,028 users who generated 14,910 conversations over five months.
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Inspect the highlighted sourceThe challenge
Electronic Health Records have improved access to patient information but substantially increased clinicians' documentation workload, and physicians must also process a large volume of information when preparing a consultation.
The solution
The hospital implemented a secure, GDPR-compliant, on-premises LLM assistant integrated into its Epic EHR. It uses Qwen3-235B (FP8) served with vLLM, with LiteLLM managing access control and request distribution, and retrieval augmented generation over structured patient data, internal and regional clinical documents, internal literature and medical literature. The interface is built on Open WebUI and embedded in Epic via the SMART on FHIR protocol, and every answer lists the sources consulted. The system runs on an on-site server with 8 NVIDIA H200 GPUs.
Reported business value
After a one-month pilot with 28 physicians across nine specialties, 64% of whom used the assistant daily, the system was deployed hospital-wide and adopted by 1,028 users who generated 14,910 conversations over five months, with more than half of clinicians using it at least weekly. Usage concentrated on information access and documentation support. The authors state they deliberately did not measure clinical outcomes or time savings.
Sources
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