NVIDIA Parabricks

NVIDIA Parabricks is a scalable genomics software suite for secondary analysis that provides GPU-accelerated versions of trusted, open-source tools, compatible with leading sequencing instruments. It increases whole-genome sequencing (WGS) analysis speed by more than 100x compared to CPU-only solutions, reducing germline analysis from about 16 hours to under 10 minutes on 4 NVIDIA RTX PRO 6000 Server Edition GPUs, and lowers WGS compute cost by up to 50%. It uses accelerated deep learning tools including Google's DeepVariant and DeepSomatic to improve accuracy for germline and somatic variants, and is freely available as a public container on NGC for use on-premises or on any cloud platform.