NVIDIA Omniverse
16 use cases using this technology
Roche scales NVIDIA AI factories globally to accelerate drug discovery, diagnostics and manufacturing
Roche
Roche is deploying more than 3,500 NVIDIA Blackwell GPUs across hybrid cloud and on-premises environments in the U.S. and Europe, expanding an existing collaboration to turn AI and accelerated computing into a core operating capability across its pharmaceutical and diagnostics businesses. AI is central to Genentech's Lab-in-the-Loop drug discovery strategy, where nearly 90% of eligible small-molecule programs integrate AI; in one program a degrader molecule for oncology was designed 25% faster, and in another AI helped deliver a backup drug candidate in seven months instead of more than two years. Roche is also using NVIDIA Omniverse to build digital twins of manufacturing sites, including its new GLP-1 facility in North Carolina, uses NVIDIA Parabricks software to enable insights across vast datasets, is evaluating the BioNeMo platform for molecular design and chemistry innovation, and uses NVIDIA NeMo Guardrails to ensure safe and reliable healthcare-grade AI.
How Bouygues Construction Drives Sustainable Building Innovation With Digital Twins
Bouygues Construction
Bouygues Construction, a global construction and infrastructure company based in France, built custom digital twin applications on NVIDIA Omniverse using the OpenUSD framework to unify 3D data from Revit, SolidWorks, and Cesium into a single collaborative environment. Using NVIDIA Isaac Sim, the company generates photorealistic synthetic training data for AI-based computer vision models covering rare or hazardous jobsite scenarios, and uses NVIDIA RTX PRO GPUs for real-time ray tracing. The approach delivered a 5x improvement in data integration speed and enabled safer job site planning through AI-driven construction site simulations and predictive scenario testing.
Roche launches NVIDIA AI factory to accelerate the development of new therapeutics and diagnostics solutions
Roche
Roche deployed 2,176 NVIDIA Blackwell GPUs on premises across the United States and Europe, bringing its combined on-premise and cloud GPU infrastructure to more than 3,500 Blackwell GPUs. The AI factory is embedded across the value chain: NVIDIA BioNeMo powers Roche's Lab-in-the-Loop strategy connecting biological and chemistry experiments with AI models in R&D; NVIDIA Omniverse-powered digital twins optimize manufacturing production lines and factory designs; accelerated computing and NVIDIA Parabricks analyze diagnostics datasets and digital pathology images; and NVIDIA NeMo Guardrails support healthcare-grade conversational AI in digital health. The expansion builds on a NVIDIA collaboration that started in 2023, and Roche's U.S. subsidiary Genentech also leverages the infrastructure for drug discovery.
BMW Group builds plant-scale digital twins with NVIDIA Omniverse, cutting vehicle aerodynamics simulation time 30x
BMW Group
BMW Group is building digital twins of its production facilities using NVIDIA Omniverse libraries, letting global production planning teams collaborate in real time, optimize the layout and design of complex manufacturing systems, and develop autonomous robot and vision AI applications prior to real-world deployment. Working with Siemens, BMW is also accelerating simulation of vehicle aerodynamics: tests on NVIDIA Grace Blackwell and CUDA-X-accelerated Simcenter Star-CCM+ software showed a 30x speedup for transient aerodynamics simulations of entire vehicle geometries, while reducing energy consumption and costs.
So nutzt Krones digitale Zwillinge und KI in der Produktion
Krones AG
Krones, working with technology-ecosystem partners Ansys (part of Synopsys), Cadfem, Microsoft Azure, Nvidia (Omniverse/OpenUSD) and SoftServe, developed 'Agentic Digital Twins' that combine physically exact real-time simulation with AI agents capable of judgment and decision-making for beverage production lines. Simulation runs that previously took three to four hours now complete in under five minutes; the AI agents test scenarios and settings, optimize workflows, and transfer the best solutions to real equipment. The digital twin was used in developing Krones' new 'Ingeniq' line concept, presented at Drinktec 2025. Compute-intensive simulations run on Microsoft Azure using Nvidia's accelerated computing platform.
How Serve Robotics Achieved 99.8% Success for Last-Mile Autonomous Delivery
Serve Robotics
Serve Robotics, which spun off from Uber in 2021, operates over 1,000 physical AI-powered sidewalk delivery robots serving over 2,500 restaurants across five cities. Its third-generation robots are simulated in NVIDIA Isaac Sim and powered by NVIDIA Jetson Orin edge AI platforms, achieving a 5x compute improvement over the prior Xavier generation and 12+ hours of battery life. The fleet has completed over 100,000 autonomous deliveries with a 99.8% completion rate, logging about 1 million miles of data monthly (nearly 170 billion image-LiDAR samples) to improve navigation and HD maps. The company plans to deploy 2,000 robots by the end of 2025.
Schaeffler Transforms Production With Digital Twins and Physical AI on NVIDIA Omniverse
Schaeffler Group
Schaeffler Group built a digital twin platform on NVIDIA Omniverse and OpenUSD, in collaboration with Wandelbots, to plan, simulate and optimize plants, machines and workflows across its 100+ global manufacturing sites. Pilot projects in e-motor assembly (China), an inverter assembly line (Germany), and Vehicle Lifetime Solutions warehouses (Europe) cut robotic task development time from hundreds of hours to half a day and reduced commissioning times for new production lines; Schaeffler plans to integrate digital twins into more than half its manufacturing sites by 2030.
Lightwheel deploys NVIDIA GR00T N1.5 humanoid robots in Geely's live automotive factory using Isaac Sim simulation
Geely
Lightwheel built a simulation-first robotics platform on NVIDIA Isaac Sim, Isaac Lab, and NVIDIA Omniverse libraries to address data scarcity and the sim-to-real gap in physical AI development. For Geely, Lightwheel fine-tuned the NVIDIA Isaac GR00T N1.5 vision-language-action foundation model to the Unitree H1 humanoid robot's morphology using simulation-generated synthetic data and DexMimicGen data augmentation, then deployed it in Geely's live automotive factory where robots autonomously perform component transportation, precise part placement on inspection trays, and coordinated dual-arm manipulation for heavy components. The platform achieves a 100:1 simulated-to-real data ratio and reduced development cycles from months to weeks.
Foxconn Develops Physical AI-Enabled Smart Factories With Digital Twins
Foxconn (Hon Hai Technology Group)
Foxconn (Hon Hai Technology Group) uses physically accurate digital twins integrating NVIDIA Omniverse libraries and OpenUSD to design, deploy, and manage high-volume production facilities, including those producing NVIDIA GB200 Grace Blackwell Superchip systems. Its Fii Omniverse Digital Twin (FODT) platform creates virtual replicas of factories, enabling simulation-driven design, real-time monitoring, and optimized operations. Using NVIDIA PhysicsNeMo AI models, Foxconn achieves 150x faster computational fluid dynamics simulations for thermal analysis (minutes vs. hours). Standardized OpenUSD-based digital twin assets enable rapid migration of entire production lines between global factories (e.g., Taiwan to Mexico). Robot workcells and AGV logistics are simulated in FODT before physical deployment: complex robotic tasks such as screw tightening and cable insertion are simulated and refined with NVIDIA Isaac Sim, Isaac Lab, FoundationPose models, and NVIDIA cuMotion, while AGV path is optimized by connecting simulations with Material Control Systems and NVIDIA cuOpt. Foxconn also built video analytics AI agents with NVIDIA Metropolis and the NVIDIA AI Blueprint for video search and summarization to monitor factory floors, and developed FoxBrain, an AI platform powered by NVIDIA NeMo trained in four weeks, described as Taiwan's first large language model with advanced reasoning capabilities. Leo Guo, General Manager of Fii Robotic Group, said the company believes it can cut factory setup and planning time by about 50%.
Hyundai Motor Group builds NVIDIA Blackwell AI factory for mobility and smart factories
Hyundai Motor Group
Hyundai Motor Group is building an AI factory using 50,000 NVIDIA Blackwell GPUs to train, validate and deploy AI for in-vehicle systems, autonomous driving, smart factories and robotics. The collaboration includes an approximately $3 billion investment with the Korean government to build a national physical AI cluster, an NVIDIA AI Technology Center and Hyundai's Physical AI Application Center. Hyundai is exploring using NVIDIA Omniverse and Cosmos on RTX PRO Servers for factory digital twins, and using NVIDIA DRIVE AGX Thor running DriveOS for driver-assistance and in-vehicle AI.
Foxconn deploys NVIDIA-powered agentic and physical AI across Taiwan's medical centers under Healthy Taiwan initiative
Foxconn
Foxconn's CoDoctor AI platform, with new AI agents including an ECG AI Agent, Corovia AI Agent and Endovia AI Agent, and Nurabot nursing collaborative robots powered by NVIDIA NemoClaw, have moved from pilot programs into clinical operations across Taiwan's major medical centers. This is part of the government-backed $1.5 billion Healthy Taiwan initiative, with a majority of Taiwan's medical centers already using AI for over 14 million patient encounters annually.
Schaeffler Group: Transforming Production With Digital Twins and Physical AI
Schaeffler Group
Schaeffler Group built a digital twin platform using NVIDIA Omniverse and OpenUSD to plan, simulate and optimize plants, machines and workflows across its global manufacturing operations, in collaboration with NVIDIA and robotics partner Wandelbots. The platform reduced commissioning times through virtual commissioning and facility layout planning, and cut robotic task development time from hundreds of hours to half a day using AI-driven simulation and training. At its Germany inverter assembly line, Schaeffler achieved reliable robotics performance after 24 hours of training and, with Wandelbots' virtual controller and reinforcement learning, refined robotic movements to within 5-6 centimeters for gearbox assembly tasks. Pilot projects are underway in China and Germany, including e-motor assembly and Vehicle Lifetime Solutions warehouses, with plans to integrate digital twins into more than half of Schaeffler's 100+ global manufacturing sites by 2030.
BMW Group scales Virtual Factory digital twins to cut production planning costs by up to 30 percent
BMW Group
BMW Group is industrialising its Virtual Factory, with production planners continuously scaling applications in digital twins of over 30 production sites built on NVIDIA Omniverse. Automated collision checks for new vehicle models that once took almost four weeks of real-world testing now take three days to simulate virtually, and production planning costs are projected to fall by up to 30 percent.
MITRE's Federal AI Sandbox accelerates government AI research with NVIDIA DGX SuperPOD
MITRE
Nonprofit MITRE built the Federal AI Sandbox, powered by NVIDIA DGX SuperPOD, to give federal sponsors an affordable, centralized space to test and deploy AI and machine learning across domains such as weather forecasting, cybersecurity, and public benefits administration. The DGX SuperPOD delivers a 300-fold performance increase over MITRE's previous AI computing capabilities and supports thousands of researchers; MITRE is using it with NVIDIA Omniverse and NVIDIA Earth-2 to develop 1-kilometer precision weather forecasts with NOAA and the National Weather Service, plus a foundational model for cybersecurity threat analysis across 190 nations.
Robot Retasking in High-Mix Manufacturing with Workr
Workr
Workr, a manufacturing AI company, uses NVIDIA Omniverse, Isaac Sim and accelerated computing to let on-site operators retask industrial robots in under five minutes via a tablet interface, eliminating weeks of traditional programming. The edge AI pipeline runs on 2x NVIDIA RTX PRO 6000 Blackwell Max-Q GPUs attached to the robot cell, using models including RAFT-Stereo, Detectron2, NVIDIA Isaac FoundationPose and NVIDIA Isaac cuMotion, trained with synthetic data generated in Isaac Sim digital twins. Deployed with customers Yuasa International and Haas Alfex.
NVIDIA DRIVE AV Software Debuts in All-New Mercedes-Benz CLA
Mercedes-Benz
The all-new Mercedes-Benz CLA, the brand's first vehicle featuring the MB.OS platform, introduces advanced driver-assistance features powered by NVIDIA's full-stack DRIVE AV software, AI infrastructure and accelerated compute, enabling enhanced level 2 point-to-point driver assistance including urban navigation, active safety and automated parking. The CLA achieved a five-star EuroNCAP safety rating.